Disease Ecology

Imperative to Vaccinate (pdf)

Lens of Disease Ecology (pdf)

Immune System: Cause of it's Own Necessity (pdf)




Utzschneider, D. T., A. Delpoux, D. Wieland, X. Huang, C. Y. Lai, M. Hofmann, R. Thimme, and S.M. Hedrick.(2018). Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1. Cell Rep 22: 3454-3467. (Full Article pdf)


Tsau, J.S., Huang, X., Lai, C.Y., Hedrick, S.M. (2018). The Effects of Dendritic Cell Hypersensitivity on Persistent Viral Infection.  J Immunol. 200(4): 1335-1346. (Full Article pdf)


Delpoux, A., Michelini, R.H., Verma, S., Lai, CY, Omilusik, K.D., Utzschneider, D.T., Redwood, A.J., Goldrath, A.W., Benedict, C.A., Hedrick, S.M. (2018). Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.  J Exp Med. 215(2): 575-594.  (Full Article pdf)


Hedrick, S. M. (2017). Understanding Immunity through the Lens of Disease Ecology. Trends Immunol 38, 888-903. (Full Article pdf)


Delpoux, A., Lai, C. Y., Hedrick, S. M., and Doedens, A. L. (2017). FOXO1 opposition of CD8+ T cell effector programming confers early memory properties and phenotypic diversity. Proc Natl Acad Sci U S A 114, E8865-E8874. (Full Article pdf)




UCSD Produced by the Hedrick Lab, 2008